A novel streptomycin and spectinomycin resistance Gene cassette occurence in E. cloacae isolated from Zhenjiang
نویسنده
چکیده
s: The aadA genes, encoding resistance to streptomycin and spectinomycin, have been found as gene cassettes in different gram-negative and gram-positive bacterial species. The present report has revealed that the sequence of a new gene, aadA5, combining with the trimethoprim resistance gene dfr17 occured in a class 1integron. The integron was identified in a nosocomial pathogen Enterobacter cloacae isolates, which indicated that integrons are specialized genetic elements that were capable of capturing, integrating and mobilizing gene-cassette by site-specific recombination and integron was a dangerous factor to lead to bacterial resistance.
منابع مشابه
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
The aadA genes, encoding resistance to streptomycin and spectinomycin, have been found as gene cassettes in different gram-negative and gram-positive bacterial species. The present study has revealed the sequence of a new gene, aadA5, integrated as a gene cassette together with the trimethoprim resistance gene dfr7 in a class 1 integron. The integron was located on a plasmid and was identified ...
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